scientificfamily
ESM3
Generative protein model debated as GPAI with systemic risk under the EU AI Act.
Levelfamily
Classscientific
Parametersnot in the notes
Contextnot in the notes
Released25 Jun 2024
Opennessunknown
Runs onnot in the notes
Statusactive
Lineage
ESM3 98B belongs to this familyscientific25 Jun 202498BESM3 open 1.4B belongs to this familyscientific25 Jun 20241.4BWhere this comes from
Parent and child relations from model cards, Hugging Face base_model fields and the genealogy tables of the research notes. Confidence and evidence are the notes' own.
Identity
- Developer
- EvolutionaryScale
- Family
- not in the notes
- Released
- 25 Jun 2024 sourcesnotesunverified
- Weights published
- –
- Record checked
- 10 Oct 2026
Where this comes from
Developer and dates from the research notes. Release date is the vendor's public announcement; weights date is when open weights were published.
Architecture and Size
- Architecture
- other Multimodal generative protein LM
- Total parameters
- – sources
- Active parameters
- –
- Checkpoint parameters
- –
- Context length
- not in the notes
- Input
- molecule
- Output
- molecule
Where this comes from
Parameter counts as the developer states them. Where the checkpoint holds a different total, both are shown (register A16).
Openness and Access
- Openness
- unknown
- Licence
- not in the notes sources
- Access routes
- not in the notes
Where this comes from
The licence file governs over registry tags and aggregator labels.
Deployment
- Runs on
- not in the notes
- Footprint
- not in the notes
- Runtimes
- not in the notes
Where this comes from
Deployment tiers and runtimes as named in the notes. Footprint is the notes' figure, not a measurement by AURION.
Indonesia
- Indonesian support
- not stated
- Regional languages
- not in the notes
- Jakarta hosting
- unknown
- Languages
- not in the notes
Where this comes from
Indonesia fields are carried on every model; unknown is an allowed value.
Benchmark Results
The notes record no benchmark result for this model.
Industry Use Cases
No industry use case links this model.
Links
DeveloperEvolutionaryScalestartup, USA
EvolutionaryScalestartup, USAModelESM3EvolutionaryScale, scientific
ESM3EvolutionaryScale, scientificUse CasesProtein Language Models and DesignHealthcareProtein Structure and ComplexesHealthcareUse cases of models in the same R&D topic; none is recorded for this model itself.
Who Runs It
PfizerContract signed, 8 Jan 2026Deployments of these use cases; none names this model.
PfizerContract signed, 8 Jan 2026Deployments of these use cases; none names this model.Models 2
Organisations 1
Sources
- arxiv.org/pdf/2605.01611 https://arxiv.org/pdf/2605.01611
- Evolutionary Scale , ESM3: Simulating 500 million years of evolution with a language model evolutionaryscale.ai https://www.evolutionaryscale.ai/blog/esm3-release
- huggingface.co/api/models/EvolutionaryScale/esm3-sm-open-v1 https://huggingface.co/api/models/EvolutionaryScale/esm3-sm-open-v1
To cite this page: Project AURION, AI Use-Cases Research & Innovation, "ESM3", https://aurion.semai.id/models/evolutionaryscale-esm3/, records of October 2026.